Coclé is a province of central Panama on the nation's southern coast. The capital is the city of Penonomé. This province was created by the Act of September 12, 1855 with the title of Department of Coclé during the presidency of Dr. Justo de Arosemena.

It became a province, Decretory Number 190, on October 20, 1985. Coclé is primarily an agricultural area, with sugar and tomatoes as major crops. The province has a number of well known beaches, such as Santa Clara, Farallon and Rio Hato, and tourist activity has increased in recent years.